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Schwann cell nodal membrane disruption triggers bystander axonal degeneration in a Guillain-Barré syndrome mouse model

In Guillain-Barré syndrome (GBS), both axonal and demyelinating variants can be mediated by complement-fixing anti–GM1 ganglioside autoantibodies that target peripheral nerve axonal and Schwann cell (SC) membranes, respectively. Critically, the extent of axonal degeneration in both variants dictates...

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Detalles Bibliográficos
Autores principales:	McGonigal, Rhona, Campbell, Clare I., Barrie, Jennifer A., Yao, Denggao, Cunningham, Madeleine E., Crawford, Colin L., Rinaldi, Simon, Rowan, Edward G., Willison, Hugh J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282931/ https://www.ncbi.nlm.nih.gov/pubmed/35671105 http://dx.doi.org/10.1172/JCI158524

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