Creatine riboside is a cancer cell–derived metabolite associated with arginine auxotrophy

The metabolic dependencies of cancer cells have substantial potential to be exploited to improve the diagnosis and treatment of cancer. Creatine riboside (CR) is identified as a urinary metabolite associated with risk and prognosis in lung and liver cancer. However, the source of high CR levels in p...

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Detalles Bibliográficos
Autores principales: Parker, Amelia L., Toulabi, Leila, Oike, Takahiro, Kanke, Yasuyuki, Patel, Daxeshkumar, Tada, Takeshi, Taylor, Sheryse, Beck, Jessica A., Bowman, Elise, Reyzer, Michelle L., Butcher, Donna, Kuhn, Skyler, Pauly, Gary T., Krausz, Kristopher W., Gonzalez, Frank J., Hussain, S. Perwez, Ambs, Stefan, Ryan, Bríd M., Wang, Xin Wei, Harris, Curtis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9282934/
https://www.ncbi.nlm.nih.gov/pubmed/35838048
http://dx.doi.org/10.1172/JCI157410

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