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IgM-associated gut bacteria in obesity and type 2 diabetes in C57BL/6 mice and humans

AIMS/HYPOTHESIS: IgM is the primary antibody produced by B cells and we hypothesise that IgM antibodies to gut microbiota may play a role in immunometabolism in obesity and type 2 diabetes. To test our hypothesis, we used B6 mice deficient in activation-induced cytidine deaminase (Aid(−/−) [also kno...

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Detalles Bibliográficos
Autores principales:	Pearson, James A., Ding, Heyuan, Hu, Changyun, Peng, Jian, Galuppo, Brittany, Wong, F. Susan, Caprio, Sonia, Santoro, Nicola, Wen, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283171/ https://www.ncbi.nlm.nih.gov/pubmed/35587276 http://dx.doi.org/10.1007/s00125-022-05711-8

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