Drug delivery for neuronopathic lysosomal storage diseases: evolving roles of the blood brain barrier and cerebrospinal fluid

Whereas significant strides have been made in the treatment of lysosomal storage diseases (LSDs), the neuronopathy associated with these diseases remains impervious mainly because of the blood-brain barrier (BBB), which prevents delivery of large molecules to the brain. However, 100 years of researc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Yuji, Minami, Kohtaro, Hirato, Toru, Tanizawa, Kazunori, Sonoda, Hiroyuki, Schmidt, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283362/
https://www.ncbi.nlm.nih.gov/pubmed/35088290
http://dx.doi.org/10.1007/s11011-021-00893-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283362/
https://www.ncbi.nlm.nih.gov/pubmed/35088290
http://dx.doi.org/10.1007/s11011-021-00893-3

Ejemplares similares