Inhibition of myeloid-derived suppressor cell arginase-1 production enhances T-cell-based immunotherapy against Cryptococcus neoformans infection

Cryptococcosis is a potentially lethal disease that is primarily caused by the fungus Cryptococcus neoformans, treatment options for cryptococcosis are limited. Here, we show glucuronoxylomannan, the major polysaccharide component of C. neoformans, induces the recruitment of neutrophilic myeloid-der...

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Detalles Bibliográficos
Autores principales: Li, Ya-Nan, Wang, Zhong-Wei, Li, Fan, Zhou, Ling-Hong, Jiang, Yan-Shan, Yu, Yao, Ma, Hui-Hui, Zhu, Li-Ping, Qu, Jie-Ming, Jia, Xin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283461/
https://www.ncbi.nlm.nih.gov/pubmed/35835754
http://dx.doi.org/10.1038/s41467-022-31723-4

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