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LRP-1 receptor combines EGFR signalling and eHsp90α autocrine to support constitutive breast cancer cell motility in absence of blood supply

Tumor cells face constant stress of ischemic (nutrient paucity and hypoxia) environment when they migrate and invade too fast to outgrow the nearest blood vessels. During the temporary loss of support from circulation, the tumor cells must act self-sufficient to survive and then to migrate to re-con...

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Detalles Bibliográficos
Autores principales: Chang, Cheng, Tang, Xin, Mosallaei, Daniel, Chen, Mei, Woodley, David T., Schönthal, Axel H., Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283467/
https://www.ncbi.nlm.nih.gov/pubmed/35835845
http://dx.doi.org/10.1038/s41598-022-16161-y