Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways

Abdominal aortic aneurysm (AAA) is a lethal disease, but no beneficial therapeutic agents have been established to date. Previously, we found that AAA formation is suppressed in microRNA (miR)-33-deficient mice compared with wild-type mice. Mice have only one miR-33, but humans have two miR-33 s, mi...

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Detalles Bibliográficos
Autores principales: Yamasaki, Tomohiro, Horie, Takahiro, Koyama, Satoshi, Nakao, Tetsushi, Baba, Osamu, Kimura, Masahiro, Sowa, Naoya, Sakamoto, Kazuhisa, Yamazaki, Kazuhiro, Obika, Satoshi, Kasahara, Yuuya, Kotera, Jun, Oka, Kozo, Fujita, Ryo, Sasaki, Takashi, Takemiya, Akihiro, Hasegawa, Koji, Minatoya, Kenji, Kimura, Takeshi, Ono, Koh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283493/
https://www.ncbi.nlm.nih.gov/pubmed/35835906
http://dx.doi.org/10.1038/s41598-022-16017-5

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