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A computational approach to quantifying miscounting of radiation-induced double-strand break immunofluorescent foci

Immunofluorescent tagging of DNA double-strand break (DSB) markers, such as γ-H2AX and other DSB repair proteins, are powerful tools in understanding biological consequences following irradiation. However, whilst the technique is widespread, there are many uncertainties related to its ability to res...

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Detalles Bibliográficos
Autores principales: Ingram, Samuel P., Warmenhoven, John-William, Henthorn, Nicholas T., Chadiwck, Amy L., Santina, Elham E., McMahon, Stephen J., Schuemann, Jan, Kirkby, Norman F., Mackay, Ranald I., Kirkby, Karen J., Merchant, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283546/
https://www.ncbi.nlm.nih.gov/pubmed/35835982
http://dx.doi.org/10.1038/s42003-022-03585-5