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A computational approach to quantifying miscounting of radiation-induced double-strand break immunofluorescent foci
Immunofluorescent tagging of DNA double-strand break (DSB) markers, such as γ-H2AX and other DSB repair proteins, are powerful tools in understanding biological consequences following irradiation. However, whilst the technique is widespread, there are many uncertainties related to its ability to res...
Autores principales: | Ingram, Samuel P., Warmenhoven, John-William, Henthorn, Nicholas T., Chadiwck, Amy L., Santina, Elham E., McMahon, Stephen J., Schuemann, Jan, Kirkby, Norman F., Mackay, Ranald I., Kirkby, Karen J., Merchant, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283546/ https://www.ncbi.nlm.nih.gov/pubmed/35835982 http://dx.doi.org/10.1038/s42003-022-03585-5 |
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