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Dampened Inflammatory Signalling and Myeloid-Derived Suppressor-Like Cell Accumulation Reduces Circulating Monocytic HLA-DR Density and May Associate With Malignancy Risk in Long-Term Renal Transplant Recipients

BACKGROUND: Malignancy is a major cause of morbidity and mortality in transplant recipients. Identification of those at highest risk could facilitate pre-emptive intervention such as reduction of immunosuppression. Reduced circulating monocytic HLA-DR density is a marker of immune depression in the...

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Detalles Bibliográficos
Autores principales:	Bottomley, Matthew J., Harden, Paul N., Wood, Kathryn J., Hester, Joanna, Issa, Fadi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283730/ https://www.ncbi.nlm.nih.gov/pubmed/35844527 http://dx.doi.org/10.3389/fimmu.2022.901273

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