Cargando…
Application of quantitative protein mass spectrometric data in the early predictive analysis of target engagement by monoclonal antibodies
Model‐informed drug discovery is endorsed by the US Food and Drug Administration (FDA) to improve the flow of medicines from bench to bedside. In the case of monoclonal antibodies, this necessitates taking into account not only the pharmacokinetic (PK) properties of the drug, but also the tissue dis...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283736/ https://www.ncbi.nlm.nih.gov/pubmed/35445800 http://dx.doi.org/10.1111/cts.13278 |