Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review

Bullous pemphigoid (BP) is a life-threatening autoimmune disease of the skin that is mainly characterized by a large range of tension blisters and intense itching of the skin. The 1-year mortality rate of BP was 23.5%. Superinfection caused by skin lesion ulceration is one of the important causes of...

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Autores principales: Cheng, Linyan, Wang, Yi, Lu, Hanzhi, Guo, Wanjun, Yan, Ge, Zhu, Jianyong, Guo, Dongjie, Li, Fulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283775/
https://www.ncbi.nlm.nih.gov/pubmed/35847802
http://dx.doi.org/10.3389/fmed.2022.938761
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author Cheng, Linyan
Wang, Yi
Lu, Hanzhi
Guo, Wanjun
Yan, Ge
Zhu, Jianyong
Guo, Dongjie
Li, Fulun
author_facet Cheng, Linyan
Wang, Yi
Lu, Hanzhi
Guo, Wanjun
Yan, Ge
Zhu, Jianyong
Guo, Dongjie
Li, Fulun
author_sort Cheng, Linyan
collection PubMed
description Bullous pemphigoid (BP) is a life-threatening autoimmune disease of the skin that is mainly characterized by a large range of tension blisters and intense itching of the skin. The 1-year mortality rate of BP was 23.5%. Superinfection caused by skin lesion ulceration is one of the important causes of disease death. Therefore, it is challenging to control infection and improve skin wound healing. Here, we report the case of an elderly woman who presented with BP and involved the oral mucosa. The patient was successfully treated with hormones combined with topical berberine, and 95% of the patients’ lesions healed completely after 1 month. In addition, we inductively analyzed the current treatments for BP to provide a reference for BP clinical treatment.
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spelling pubmed-92837752022-07-16 Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review Cheng, Linyan Wang, Yi Lu, Hanzhi Guo, Wanjun Yan, Ge Zhu, Jianyong Guo, Dongjie Li, Fulun Front Med (Lausanne) Medicine Bullous pemphigoid (BP) is a life-threatening autoimmune disease of the skin that is mainly characterized by a large range of tension blisters and intense itching of the skin. The 1-year mortality rate of BP was 23.5%. Superinfection caused by skin lesion ulceration is one of the important causes of disease death. Therefore, it is challenging to control infection and improve skin wound healing. Here, we report the case of an elderly woman who presented with BP and involved the oral mucosa. The patient was successfully treated with hormones combined with topical berberine, and 95% of the patients’ lesions healed completely after 1 month. In addition, we inductively analyzed the current treatments for BP to provide a reference for BP clinical treatment. Frontiers Media S.A. 2022-07-01 /pmc/articles/PMC9283775/ /pubmed/35847802 http://dx.doi.org/10.3389/fmed.2022.938761 Text en Copyright © 2022 Cheng, Wang, Lu, Guo, Yan, Zhu, Guo and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Cheng, Linyan
Wang, Yi
Lu, Hanzhi
Guo, Wanjun
Yan, Ge
Zhu, Jianyong
Guo, Dongjie
Li, Fulun
Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review
title Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review
title_full Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review
title_fullStr Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review
title_full_unstemmed Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review
title_short Successful Treatment of Bullous Pemphigoid Lesions by Berberine Stamp Therapy: A Case Report and Literature Review
title_sort successful treatment of bullous pemphigoid lesions by berberine stamp therapy: a case report and literature review
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283775/
https://www.ncbi.nlm.nih.gov/pubmed/35847802
http://dx.doi.org/10.3389/fmed.2022.938761
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