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Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing
The Oxford Nanopore (ONT) platform provides portable and rapid genome sequencing, and its ability to natively profile DNA methylation without complex sample processing is attractive for point-of-care real-time sequencing. We recently demonstrated ONT shallow whole-genome sequencing to detect copy nu...
Autores principales: | Katsman, Efrat, Orlanski, Shari, Martignano, Filippo, Fox-Fisher, Ilana, Shemer, Ruth, Dor, Yuval, Zick, Aviad, Eden, Amir, Petrini, Iacopo, Conticello, Silvestro G., Berman, Benjamin P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283844/ https://www.ncbi.nlm.nih.gov/pubmed/35841107 http://dx.doi.org/10.1186/s13059-022-02710-1 |
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