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Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella

Few cases of Hypervirulent Klebsiella Pneumonia (HvKP) have been described. Even fewer cases with renal abscess and metastatic pulmonary spread are reported. Typically, prompt introduction of intravenous antibiotics leads to clinical resolution and more invasive measures of source control are rarely...

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Detalles Bibliográficos
Autores principales: Neerhut, Thomas, Ninan, John, Crozier, Jack, Lawson, Malcolm, Rhee, Handoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283878/
https://www.ncbi.nlm.nih.gov/pubmed/35846515
http://dx.doi.org/10.1016/j.eucr.2022.102157
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author Neerhut, Thomas
Ninan, John
Crozier, Jack
Lawson, Malcolm
Rhee, Handoo
author_facet Neerhut, Thomas
Ninan, John
Crozier, Jack
Lawson, Malcolm
Rhee, Handoo
author_sort Neerhut, Thomas
collection PubMed
description Few cases of Hypervirulent Klebsiella Pneumonia (HvKP) have been described. Even fewer cases with renal abscess and metastatic pulmonary spread are reported. Typically, prompt introduction of intravenous antibiotics leads to clinical resolution and more invasive measures of source control are rarely required. To date only one other case of disseminated metastatic HvKP requiring nephrectomy for infective source control is described. Here we present a rare case of metastatic HvKP refractory to intravenous antimicrobial therapy in an immunocompromised newly diagnosed diabetic patient. Specifically, we seek to illustrate the rapid effectiveness of surgical intervention following a poor response to initial treatment.
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spelling pubmed-92838782022-07-16 Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella Neerhut, Thomas Ninan, John Crozier, Jack Lawson, Malcolm Rhee, Handoo Urol Case Rep Inflammation and Infection Few cases of Hypervirulent Klebsiella Pneumonia (HvKP) have been described. Even fewer cases with renal abscess and metastatic pulmonary spread are reported. Typically, prompt introduction of intravenous antibiotics leads to clinical resolution and more invasive measures of source control are rarely required. To date only one other case of disseminated metastatic HvKP requiring nephrectomy for infective source control is described. Here we present a rare case of metastatic HvKP refractory to intravenous antimicrobial therapy in an immunocompromised newly diagnosed diabetic patient. Specifically, we seek to illustrate the rapid effectiveness of surgical intervention following a poor response to initial treatment. Elsevier 2022-07-08 /pmc/articles/PMC9283878/ /pubmed/35846515 http://dx.doi.org/10.1016/j.eucr.2022.102157 Text en Crown Copyright © 2022 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Inflammation and Infection
Neerhut, Thomas
Ninan, John
Crozier, Jack
Lawson, Malcolm
Rhee, Handoo
Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella
title Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella
title_full Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella
title_fullStr Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella
title_full_unstemmed Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella
title_short Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella
title_sort urgent nephrectomy for rapidly progressive disseminated metastatic hypermucoid klebsiella
topic Inflammation and Infection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283878/
https://www.ncbi.nlm.nih.gov/pubmed/35846515
http://dx.doi.org/10.1016/j.eucr.2022.102157
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