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Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella
Few cases of Hypervirulent Klebsiella Pneumonia (HvKP) have been described. Even fewer cases with renal abscess and metastatic pulmonary spread are reported. Typically, prompt introduction of intravenous antibiotics leads to clinical resolution and more invasive measures of source control are rarely...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283878/ https://www.ncbi.nlm.nih.gov/pubmed/35846515 http://dx.doi.org/10.1016/j.eucr.2022.102157 |
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author | Neerhut, Thomas Ninan, John Crozier, Jack Lawson, Malcolm Rhee, Handoo |
author_facet | Neerhut, Thomas Ninan, John Crozier, Jack Lawson, Malcolm Rhee, Handoo |
author_sort | Neerhut, Thomas |
collection | PubMed |
description | Few cases of Hypervirulent Klebsiella Pneumonia (HvKP) have been described. Even fewer cases with renal abscess and metastatic pulmonary spread are reported. Typically, prompt introduction of intravenous antibiotics leads to clinical resolution and more invasive measures of source control are rarely required. To date only one other case of disseminated metastatic HvKP requiring nephrectomy for infective source control is described. Here we present a rare case of metastatic HvKP refractory to intravenous antimicrobial therapy in an immunocompromised newly diagnosed diabetic patient. Specifically, we seek to illustrate the rapid effectiveness of surgical intervention following a poor response to initial treatment. |
format | Online Article Text |
id | pubmed-9283878 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-92838782022-07-16 Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella Neerhut, Thomas Ninan, John Crozier, Jack Lawson, Malcolm Rhee, Handoo Urol Case Rep Inflammation and Infection Few cases of Hypervirulent Klebsiella Pneumonia (HvKP) have been described. Even fewer cases with renal abscess and metastatic pulmonary spread are reported. Typically, prompt introduction of intravenous antibiotics leads to clinical resolution and more invasive measures of source control are rarely required. To date only one other case of disseminated metastatic HvKP requiring nephrectomy for infective source control is described. Here we present a rare case of metastatic HvKP refractory to intravenous antimicrobial therapy in an immunocompromised newly diagnosed diabetic patient. Specifically, we seek to illustrate the rapid effectiveness of surgical intervention following a poor response to initial treatment. Elsevier 2022-07-08 /pmc/articles/PMC9283878/ /pubmed/35846515 http://dx.doi.org/10.1016/j.eucr.2022.102157 Text en Crown Copyright © 2022 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Inflammation and Infection Neerhut, Thomas Ninan, John Crozier, Jack Lawson, Malcolm Rhee, Handoo Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella |
title | Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella |
title_full | Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella |
title_fullStr | Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella |
title_full_unstemmed | Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella |
title_short | Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella |
title_sort | urgent nephrectomy for rapidly progressive disseminated metastatic hypermucoid klebsiella |
topic | Inflammation and Infection |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283878/ https://www.ncbi.nlm.nih.gov/pubmed/35846515 http://dx.doi.org/10.1016/j.eucr.2022.102157 |
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