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Multi-scale phase separation by explosive percolation with single-chromatin loop resolution

The 2 m-long human DNA is tightly intertwined into the cell nucleus of the size of 10 μm. The DNA packing is explained by folding of chromatin fiber. This folding leads to the formation of such hierarchical structures as: chromosomal territories, compartments; densely-packed genomic regions known as...

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Detalles Bibliográficos
Autores principales: Sengupta, Kaustav, Denkiewicz, Michał, Chiliński, Mateusz, Szczepińska, Teresa, Mollah, Ayatullah Faruk, Korsak, Sevastianos, D'Souza, Raissa, Ruan, Yijun, Plewczynski, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283880/
https://www.ncbi.nlm.nih.gov/pubmed/35860407
http://dx.doi.org/10.1016/j.csbj.2022.06.063