Cargando…

Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis

Abnormal expression of Forkhead box protein M1 (FOXM1) and serine/threonine kinase Budding uninhibited by benzimidazoles 1 (BUB1B) contributes to the development and progression of several cancers, including chronic myelogenous leukemia (CML). However, the molecular mechanism of the FOXM1/BUB1B regu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuttikrishnan, Shilpa, Masoodi, Tariq, Sher, Gulab, Bhat, Ajaz A., Patil, Kalyani, El-Elimat, Tamam, Oberlies, Nicholas H., Pearce, Cedric J., Haris, Mohmmad, Ahmad, Aamir, Alali, Feras Q., Uddin, Shahab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9283897/ https://www.ncbi.nlm.nih.gov/pubmed/35847923 http://dx.doi.org/10.3389/fonc.2022.929996

Ejemplares similares

Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines
por: Prabhu, Kirti S., et al.
Publicado: (2018)

Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines
por: Prabhu, Kirti S., et al.
Publicado: (2019)

The FOXM1/BUB1B signaling pathway is essential for the tumorigenicity and radioresistance of glioblastoma
por: Ma, Qing, et al.
Publicado: (2017)

Expression and prognosis analyses of BUB1, BUB1B and BUB3 in human sarcoma
por: Long, Zeling, et al.
Publicado: (2021)

Acceptance and attitudes toward COVID-19 vaccines: A cross-sectional study from Jordan
por: El-Elimat, Tamam, et al.
Publicado: (2021)

Evaluation of the Effect of Hypericum triquetrifolium Turra on Memory Impairment Induced by Chronic Psychosocial Stress in Rats: Role of BDNF
por: Alzoubi, Karem H, et al.
Publicado: (2020)

Evaluation of culture media for the production of secondary metabolites in a natural products screening program
por: VanderMolen, Karen M, et al.
Publicado: (2013)

BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability
por: Tang, Xiaozhu, et al.
Publicado: (2021)

7-O-Methylpunctatin, a Novel Homoisoflavonoid, Inhibits Phenotypic Switch of Human Arteriolar Smooth Muscle Cells
por: Fardoun, Manal, et al.
Publicado: (2019)

Greensporones: Resorcylic Acid Lactones from an Aquatic Halenospora sp.
por: El-Elimat, Tamam, et al.
Publicado: (2014)

Enhanced dereplication of fungal cultures via use of mass defect filtering
por: Paguigan, Noemi D, et al.
Publicado: (2017)

BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) promotes lung adenocarcinoma by interacting with Zinc Finger Protein ZNF143 and regulating glycolysis
por: Zhou, Xiaolei, et al.
Publicado: (2022)

Requirement for BUB1B/BUBR1 in tumor progression of lung adenocarcinoma
por: Chen, Honglin, et al.
Publicado: (2015)

PCS/MVA syndrome caused by an Alu insertion in the BUB1B gene
por: Kato, Maki, et al.
Publicado: (2017)

Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis
por: Hadders, Michael A., et al.
Publicado: (2020)

BuB: a builder-booster model for link prediction on knowledge graphs
por: Soltanshahi, Mohammad Ali, et al.
Publicado: (2023)

Dereplicating and Spatial Mapping of Secondary Metabolites from Fungal Cultures in Situ
por: Sica, Vincent P., et al.
Publicado: (2015)

Scaffold Diversity of Fungal Metabolites
por: González-Medina, Mariana, et al.
Publicado: (2017)

Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway
por: Akhtar, Sabah, et al.
Publicado: (2022)

PTPROt-mediated regulation of p53/Foxm1 suppresses leukemic phenotype in a CLL mouse model
por: Motiwala, Tasneem, et al.
Publicado: (2014)

The Human Homologue of Bub3 Is Required for Kinetochore Localization of Bub1 and a Mad3/Bub1-related Protein Kinase
por: Taylor, Stephen S., et al.
Publicado: (1998)

Clinical value and potential mechanisms of BUB1B up-regulation in nasopharyngeal carcinoma
por: Qin, Li-Ting, et al.
Publicado: (2022)

Deregulation of FoxM1b leads to tumour metastasis
por: Park, Hyun Jung, et al.
Publicado: (2011)

Silymarin Ameliorates Diabetes-Induced Proangiogenic Response in Brain Endothelial Cells through a GSK-3β Inhibition-Induced Reduction of VEGF Release
por: Alhusban, Ahmed, et al.
Publicado: (2017)

Potential therapeutic targets of Guggulsterone in cancer
por: Bhat, Ajaz A., et al.
Publicado: (2017)

BUB1, BUB1B, CCNA2, and CDCA8, along with miR-524-5p, as clinically relevant biomarkers for the diagnosis and treatment of endometrial carcinoma
por: Hao, Qirong, et al.
Publicado: (2023)

Targeting of X-linked inhibitor of apoptosis protein and PI3-kinase/AKT signaling by embelin suppresses growth of leukemic cells
por: Prabhu, Kirti S., et al.
Publicado: (2017)

Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans
por: Kim, Taekyung, et al.
Publicado: (2015)

Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint
por: Zhang, Gang, et al.
Publicado: (2015)

Differential requirement for Bub1 and Bub3 in regulation of meiotic versus mitotic chromosome segregation
por: Cairo, Gisela, et al.
Publicado: (2020)

Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation
por: Ricke, Robin M., et al.
Publicado: (2011)

Association between polymorphisms in segregation genes BUB1B and TTK and gastric cancer risk
por: Hudler, Petra, et al.
Publicado: (2016)

BUB1B promotes extrahepatic cholangiocarcinoma progression via JNK/c-Jun pathways
por: Jiao, Chen Yu, et al.
Publicado: (2021)

Understanding Reciprocity Among University Students in Low-Resource Settings: Validation and Measurement Using a Mixed-Methods Approach
por: AbuAlSamen, Mahmoud M., et al.
Publicado: (2022)

Polyhydroxyanthraquinones as Quorum Sensing Inhibitors from the Guttates of Penicillium restrictum and Their Analysis by Desorption Electrospray Ionization Mass Spectrometry
por: Figueroa, Mario, et al.
Publicado: (2014)

Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle)
por: Raja, Huzefa A., et al.
Publicado: (2015)

Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshin
por: Windecker, Hanna, et al.
Publicado: (2009)

Correction: Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans
por: Kim, Taekyung, et al.
Publicado: (2016)

A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint
por: Overlack, Katharina, et al.
Publicado: (2015)

BubR1 recruitment to the kinetochore via Bub1 enhances spindle assembly checkpoint signaling
por: Banerjee, Anand, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j719gff1bf6g35elhoid0kadcf