Soft, Dynamic Hydrogel Confinement Improves Kidney Organoid Lumen Morphology and Reduces Epithelial–Mesenchymal Transition in Culture

Pluripotent stem cell‐derived kidney organoids offer a promising solution to renal failure, yet current organoid protocols often lead to off‐target cells and phenotypic alterations, preventing maturity. Here, various dynamic hydrogel architectures are created, conferring a controlled and biomimetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruiter, Floor A. A., Morgan, Francis L. C., Roumans, Nadia, Schumacher, Anika, Slaats, Gisela G., Moroni, Lorenzo, LaPointe, Vanessa L. S., Baker, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284132/
https://www.ncbi.nlm.nih.gov/pubmed/35567354
http://dx.doi.org/10.1002/advs.202200543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284132/
https://www.ncbi.nlm.nih.gov/pubmed/35567354
http://dx.doi.org/10.1002/advs.202200543

Ejemplares similares