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A Space‐Time Conversion Vehicle for Programmed Multi‐Drugs Delivery into Pancreatic Tumor to Overcome Matrix and Reflux Barriers
The numerous biological barriers, which limit pharmacotherapy of pancreatic carcinoma, including inadequate drug accumulation in the tumor environment, a dense extracellular matrix (ECM) and efficient drug‐efflux mechanisms, illustrate the requirement of multifunctional delivery systems to overcome...
Autores principales: | Huo, Taotao, Zhang, Xiaoyi, Qian, Min, Nie, Huifang, Liang, Dong, Lin, Chenteng, Yang, Yafeng, Guo, Wei, Lächelt, Ulrich, Huang, Rongqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284157/ https://www.ncbi.nlm.nih.gov/pubmed/35508899 http://dx.doi.org/10.1002/advs.202200608 |
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