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Cyclic Mechanical Stresses Alter Erythrocyte Membrane Composition and Microstructure and Trigger Macrophage Phagocytosis

Red blood cells (RBCs) are cleared from the circulation when they become damaged or display aging signals targeted by macrophages. This process occurs mainly in the spleen, where blood flows through submicrometric constrictions called inter‐endothelial slits (IES), subjecting RBCs to large‐amplitude...

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Detalles Bibliográficos
Autores principales: Garcia‐Herreros, Antoni, Yeh, Yi‐Ting, Peng, Zhangli, del Álamo, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284186/
https://www.ncbi.nlm.nih.gov/pubmed/35508805
http://dx.doi.org/10.1002/advs.202201481