Cargando…
Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos
IMPORTANCE: The Mediterranean diet may reduce the burden of Alzheimer disease and other associated dementias in Hispanic or Latino people. OBJECTIVE: To investigate the association of a Mediterranean diet with cognitive performance among community-dwelling Hispanic or Latino adults. DESIGN, SETTING,...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284337/ https://www.ncbi.nlm.nih.gov/pubmed/35834250 http://dx.doi.org/10.1001/jamanetworkopen.2022.21982 |
_version_ | 1784747538747752448 |
---|---|
author | Moustafa, Bayan Trifan, Gabriela Isasi, Carmen R. Lipton, Richard B. Sotres-Alvarez, Daniela Cai, Jianwen Tarraf, Wassim Stickel, Ariana Mattei, Josiemer Talavera, Gregory A. Daviglus, Martha L. González, Hector M. Testai, Fernando D. |
author_facet | Moustafa, Bayan Trifan, Gabriela Isasi, Carmen R. Lipton, Richard B. Sotres-Alvarez, Daniela Cai, Jianwen Tarraf, Wassim Stickel, Ariana Mattei, Josiemer Talavera, Gregory A. Daviglus, Martha L. González, Hector M. Testai, Fernando D. |
author_sort | Moustafa, Bayan |
collection | PubMed |
description | IMPORTANCE: The Mediterranean diet may reduce the burden of Alzheimer disease and other associated dementias in Hispanic or Latino people. OBJECTIVE: To investigate the association of a Mediterranean diet with cognitive performance among community-dwelling Hispanic or Latino adults. DESIGN, SETTING, AND PARTICIPANTS: This cohort study analyzed data from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) and the Study of Latinos–Investigation of Neurocognitive Aging (SOL–INCA), an HCHS/SOL ancillary study. Cognition tests were administered in the HCHS/SOL from March 2008 to June 2011 (visit 1) and in the SOL–INCA from October 2015 to March 2018 (visit 2). Participants included in the present study had completed a diet assessment at visit 1 and neurocognitive evaluations at visits 1 and 2. Data were analyzed from September 2021 to May 2022. EXPOSURES: Mediterranean diet adherence was ascertained using the Mediterranean diet score (MDS) and was categorized as low (MDS: 0-4 points), moderate (MDS: 5-6 points), or high (MDS: 7-9 points). The mean of two 24-hour dietary recalls was used to calculate the MDS. MAIN OUTCOMES AND MEASURES: Cognitive change between visits 1 and 2 was calculated by subtracting the cognitive score at visit 2 from the cognitive score at visit 1 and adjusting by the time elapsed between visits and cognitive score at visit 1. Neurocognitive tests administered were Brief Spanish-English Verbal Learning Test (B-SEVLT) Sum, B-SEVLT Recall, word fluency, and Digit Symbol Substitution Test (DSST). Results of each test were z score–transformed and the means were averaged to create a global cognition score. Complex sample linear regression analysis was used to ascertain the association between MDS and neurocognitive performance at each visit and neurocognitive change. RESULTS: A total of 6321 participants (mean [SE] age, 56.1 [0.18] years at visit 1; n = 4077 women [57.8%]) were included. Mediterranean diet adherence weighted frequencies were 35.8% (n = 2112 of 6321) for the low adherence group, 45.4% (n = 2795) for the moderate adherence group, and 18.8% (n = 1414) for the high adherence group. In the fully adjusted model, z score–transformed cognitive scores at visit 1 in the high vs low adherence groups were higher for B-SEVLT Sum (β = 0.11; 95% CI, 0.02-0.20), B-SEVLT Recall (β = 0.16; 95% CI, 0.07-0.25), and global cognition (β = 0.10; 95% CI, 0.04-0.16) tests. In the mean follow-up time of 7 years, cognitive change in the high vs low adherence groups was less pronounced for B-SEVLT Sum (β = 0.12; 95% CI, 0.05-0.20) and B-SEVLT Recall (β = 0.14; 95% CI, 0.05-0.23), but not for word fluency, DSST score, or global cognition score. CONCLUSIONS AND RELEVANCE: Results of this cohort study suggested that high adherence to a Mediterranean diet was associated with better cognitive performance and decreased 7-year learning and memory decline among middle-aged and older Hispanic or Latino adults. Culturally tailored Mediterranean diet may reduce the risk of cognitive decline and Alzheimer disease in this population. |
format | Online Article Text |
id | pubmed-9284337 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | American Medical Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-92843372022-08-01 Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos Moustafa, Bayan Trifan, Gabriela Isasi, Carmen R. Lipton, Richard B. Sotres-Alvarez, Daniela Cai, Jianwen Tarraf, Wassim Stickel, Ariana Mattei, Josiemer Talavera, Gregory A. Daviglus, Martha L. González, Hector M. Testai, Fernando D. JAMA Netw Open Original Investigation IMPORTANCE: The Mediterranean diet may reduce the burden of Alzheimer disease and other associated dementias in Hispanic or Latino people. OBJECTIVE: To investigate the association of a Mediterranean diet with cognitive performance among community-dwelling Hispanic or Latino adults. DESIGN, SETTING, AND PARTICIPANTS: This cohort study analyzed data from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) and the Study of Latinos–Investigation of Neurocognitive Aging (SOL–INCA), an HCHS/SOL ancillary study. Cognition tests were administered in the HCHS/SOL from March 2008 to June 2011 (visit 1) and in the SOL–INCA from October 2015 to March 2018 (visit 2). Participants included in the present study had completed a diet assessment at visit 1 and neurocognitive evaluations at visits 1 and 2. Data were analyzed from September 2021 to May 2022. EXPOSURES: Mediterranean diet adherence was ascertained using the Mediterranean diet score (MDS) and was categorized as low (MDS: 0-4 points), moderate (MDS: 5-6 points), or high (MDS: 7-9 points). The mean of two 24-hour dietary recalls was used to calculate the MDS. MAIN OUTCOMES AND MEASURES: Cognitive change between visits 1 and 2 was calculated by subtracting the cognitive score at visit 2 from the cognitive score at visit 1 and adjusting by the time elapsed between visits and cognitive score at visit 1. Neurocognitive tests administered were Brief Spanish-English Verbal Learning Test (B-SEVLT) Sum, B-SEVLT Recall, word fluency, and Digit Symbol Substitution Test (DSST). Results of each test were z score–transformed and the means were averaged to create a global cognition score. Complex sample linear regression analysis was used to ascertain the association between MDS and neurocognitive performance at each visit and neurocognitive change. RESULTS: A total of 6321 participants (mean [SE] age, 56.1 [0.18] years at visit 1; n = 4077 women [57.8%]) were included. Mediterranean diet adherence weighted frequencies were 35.8% (n = 2112 of 6321) for the low adherence group, 45.4% (n = 2795) for the moderate adherence group, and 18.8% (n = 1414) for the high adherence group. In the fully adjusted model, z score–transformed cognitive scores at visit 1 in the high vs low adherence groups were higher for B-SEVLT Sum (β = 0.11; 95% CI, 0.02-0.20), B-SEVLT Recall (β = 0.16; 95% CI, 0.07-0.25), and global cognition (β = 0.10; 95% CI, 0.04-0.16) tests. In the mean follow-up time of 7 years, cognitive change in the high vs low adherence groups was less pronounced for B-SEVLT Sum (β = 0.12; 95% CI, 0.05-0.20) and B-SEVLT Recall (β = 0.14; 95% CI, 0.05-0.23), but not for word fluency, DSST score, or global cognition score. CONCLUSIONS AND RELEVANCE: Results of this cohort study suggested that high adherence to a Mediterranean diet was associated with better cognitive performance and decreased 7-year learning and memory decline among middle-aged and older Hispanic or Latino adults. Culturally tailored Mediterranean diet may reduce the risk of cognitive decline and Alzheimer disease in this population. American Medical Association 2022-07-14 /pmc/articles/PMC9284337/ /pubmed/35834250 http://dx.doi.org/10.1001/jamanetworkopen.2022.21982 Text en Copyright 2022 Moustafa B et al. JAMA Network Open. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the CC-BY License. |
spellingShingle | Original Investigation Moustafa, Bayan Trifan, Gabriela Isasi, Carmen R. Lipton, Richard B. Sotres-Alvarez, Daniela Cai, Jianwen Tarraf, Wassim Stickel, Ariana Mattei, Josiemer Talavera, Gregory A. Daviglus, Martha L. González, Hector M. Testai, Fernando D. Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos |
title | Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos |
title_full | Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos |
title_fullStr | Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos |
title_full_unstemmed | Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos |
title_short | Association of Mediterranean Diet With Cognitive Decline Among Diverse Hispanic or Latino Adults From the Hispanic Community Health Study/Study of Latinos |
title_sort | association of mediterranean diet with cognitive decline among diverse hispanic or latino adults from the hispanic community health study/study of latinos |
topic | Original Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284337/ https://www.ncbi.nlm.nih.gov/pubmed/35834250 http://dx.doi.org/10.1001/jamanetworkopen.2022.21982 |
work_keys_str_mv | AT moustafabayan associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT trifangabriela associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT isasicarmenr associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT liptonrichardb associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT sotresalvarezdaniela associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT caijianwen associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT tarrafwassim associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT stickelariana associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT matteijosiemer associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT talaveragregorya associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT daviglusmarthal associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT gonzalezhectorm associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos AT testaifernandod associationofmediterraneandietwithcognitivedeclineamongdiversehispanicorlatinoadultsfromthehispaniccommunityhealthstudystudyoflatinos |