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Natural-product-inspired design and synthesis of thiolated coenzyme Q analogs as promising agents against Gram-positive bacterial strains: insights into structure–activity relationship, activity profile, mode of action, and molecular docking
In an attempt to develop effective and potentially active antibacterial and/or antifungal agents, we designed, synthesized, and characterized thiolated CoQ analogs (CoQ1–8) with an extensive antimicrobial study. The antimicrobial profile of these analogs was determined using four Gram-negative bacte...
Autores principales: | Yıldırım, Hatice, Yıldız, Mahmut, Bayrak, Nilüfer, Mataracı-Kara, Emel, Özbek-Çelik, Berna, Otsuka, Masami, Fujita, Mikako, Radwan, Mohamed O., TuYuN, Amaç Fatih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284347/ https://www.ncbi.nlm.nih.gov/pubmed/35919160 http://dx.doi.org/10.1039/d2ra02136f |
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