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Core shell stationary phase for a novel separation of some COVID-19 used drugs by UPLC-MS/MS Method: Study of grapefruit consumption impact on their pharmacokinetics in rats

A sensitive and selective UPLC-MS/MS method was developed for the synchronized determination of four drugs used in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), namely, azithromycin, apixaban, dexamethasone, and favipiravir in rat plasma. using a Poroshell 120 EC-C18 column (50 mm × ...

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Detalles Bibliográficos
Autores principales: Tarek Mahmoud, Sally, Moffid, Marwa A., Sayed, Rawda M., Mostafa, Eman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284531/
https://www.ncbi.nlm.nih.gov/pubmed/35855210
http://dx.doi.org/10.1016/j.microc.2022.107769