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Non-Antimicrobial Adjuvant Therapy Using Ticagrelor Reduced Biofilm-Related Staphylococcus aureus Prosthetic Joint Infection

Background: Prosthetic joint infection (PJI), frequently caused by Staphylococcus aureus, leads to a significant arthroplasty failure rate. Biofilm is a crucial virulence factor of S. aureus that is intrinsic to the pathogenesis of PJI. Biofilm-related infections are recalcitrant to antibiotic treat...

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Detalles Bibliográficos
Autores principales: Pant, Narayan, Miranda-Hernandez, Socorro, Rush, Catherine, Warner, Jeffrey, Eisen, Damon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284533/
https://www.ncbi.nlm.nih.gov/pubmed/35846990
http://dx.doi.org/10.3389/fphar.2022.927783