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Solid-State NMR Reveals Asymmetric ATP Hydrolysis in the Multidrug ABC Transporter BmrA

[Image: see text] The detailed mechanism of ATP hydrolysis in ATP-binding cassette (ABC) transporters is still not fully understood. Here, we employed (31)P solid-state NMR to probe the conformational changes and dynamics during the catalytic cycle by locking the multidrug ABC transporter BmrA in pr...

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Detalles Bibliográficos
Autores principales:	Lacabanne, Denis, Wiegand, Thomas, Di Cesare, Margot, Orelle, Cédric, Ernst, Matthias, Jault, Jean-Michel, Meier, Beat H., Böckmann, Anja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284561/ https://www.ncbi.nlm.nih.gov/pubmed/35776907 http://dx.doi.org/10.1021/jacs.2c04287

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