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MiR-574-3p inhibits glucose toxicity-induced pancreatic β-cell dysfunction by suppressing PRMT1

BACKGROUND: Pancreatic β-cell dysfunction is commonly observed in patients with type 2 diabetes mellitus. Protein arginine methyltransferase 1 (PRMT1) plays an important role in pancreatic β-cell dysfunction. However, the detailed mechanisms remain largely unknown. METHODS: RT-qPCR, western blotting...

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Detalles Bibliográficos
Autores principales: Lv, Lixia, Wang, Xiumin, Shen, Jinhua, Cao, Ying, Zhang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284709/
https://www.ncbi.nlm.nih.gov/pubmed/35841066
http://dx.doi.org/10.1186/s13098-022-00869-y

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