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MiR-574-3p inhibits glucose toxicity-induced pancreatic β-cell dysfunction by suppressing PRMT1
BACKGROUND: Pancreatic β-cell dysfunction is commonly observed in patients with type 2 diabetes mellitus. Protein arginine methyltransferase 1 (PRMT1) plays an important role in pancreatic β-cell dysfunction. However, the detailed mechanisms remain largely unknown. METHODS: RT-qPCR, western blotting...
Autores principales: | Lv, Lixia, Wang, Xiumin, Shen, Jinhua, Cao, Ying, Zhang, Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284709/ https://www.ncbi.nlm.nih.gov/pubmed/35841066 http://dx.doi.org/10.1186/s13098-022-00869-y |
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