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Organ-specific extracellular matrix directs trans-differentiation of mesenchymal stem cells and formation of salivary gland-like organoids in vivo
BACKGROUND: Current treatments for salivary gland (SG) hypofunction are palliative and do not address the underlying cause or progression of the disease. SG-derived stem cells have the potential to treat SG hypofunction, but their isolation is challenging, especially when the tissue has been damaged...
Autores principales: | Tran, Olivia N., Wang, Hanzhou, Li, Shengxian, Malakhov, Andrey, Sun, Yuyang, Abdul Azees, Parveez A., Gonzalez, Aaron O., Cao, Brian, Marinkovic, Milos, Singh, Brij B., Dean, David D., Yeh, Chih-Ko, Chen, Xiao-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284714/ https://www.ncbi.nlm.nih.gov/pubmed/35841112 http://dx.doi.org/10.1186/s13287-022-02993-y |
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