Organ-specific extracellular matrix directs trans-differentiation of mesenchymal stem cells and formation of salivary gland-like organoids in vivo

BACKGROUND: Current treatments for salivary gland (SG) hypofunction are palliative and do not address the underlying cause or progression of the disease. SG-derived stem cells have the potential to treat SG hypofunction, but their isolation is challenging, especially when the tissue has been damaged...

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Detalles Bibliográficos
Autores principales: Tran, Olivia N., Wang, Hanzhou, Li, Shengxian, Malakhov, Andrey, Sun, Yuyang, Abdul Azees, Parveez A., Gonzalez, Aaron O., Cao, Brian, Marinkovic, Milos, Singh, Brij B., Dean, David D., Yeh, Chih-Ko, Chen, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284714/
https://www.ncbi.nlm.nih.gov/pubmed/35841112
http://dx.doi.org/10.1186/s13287-022-02993-y

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