Study protocol of a single-arm phase 2 study evaluating the preventive effect of topical hydrocortisone for capecitabine-induced hand-foot syndrome in colorectal cancer patients receiving adjuvant chemotherapy with capecitabine plus oxaliplatin (T-CRACC study)

BACKGROUNDS: Clinical evidence of the preventive effectiveness of medium-class topical corticosteroids for capecitabine-induced hand foot syndrome (HFS) is limited. Although the pathogenesis and mechanism of HFS are unclear, inflammatory reactions are thought to be involved in HFS development. This...

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Detalles Bibliográficos
Autores principales: Iimura, Yohei, Furukawa, Naoki, Ishibashi, Masaaki, Ahiko, Yuka, Tanabe, Taro, Aikou, Susumu, Shida, Dai, Nojima, Masanori, Kuroda, Seiichiro, Boku, Narikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284769/
https://www.ncbi.nlm.nih.gov/pubmed/35836104
http://dx.doi.org/10.1186/s12876-022-02411-w

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