Circular RNA circPOLR2A promotes clear cell renal cell carcinoma progression by facilitating the UBE3C-induced ubiquitination of PEBP1 and, thereby, activating the ERK signaling pathway

BACKGROUND: Increasing evidence has demonstrated that circular RNAs (circRNAs) are implicated in cancer progression. However, the aberrant expression and biological functions of circRNAs in clear cell renal cell carcinoma (cRCC) remain largely elusive. METHOD: Differentially expressed circRNAs in cR...

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Detalles Bibliográficos
Autores principales: Xu, Zhipeng, Chen, Shuqiu, Liu, Ruiji, Chen, Hui, Xu, Bin, Xu, Weizhang, Chen, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284792/
https://www.ncbi.nlm.nih.gov/pubmed/35840930
http://dx.doi.org/10.1186/s12943-022-01607-8

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