Exosomal miR-132-3p from mesenchymal stromal cells improves synaptic dysfunction and cognitive decline in vascular dementia

BACKGROUND/AIMS: Vascular dementia (VD) results in cognition and memory deficit. Exosomes and their carried microRNAs (miRs) contribute to the neuroprotective effects of mesenchymal stromal cells, and miR-132-3p plays a key role in neuron plasticity. Here, we investigated the role and underlying mec...

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Detalles Bibliográficos
Autores principales: Ma, Xiaotang, Wang, Yan, Shi, Yumeng, Li, Suqing, Liu, Jinhua, Li, Xiangyong, Zhong, Wangtao, Pan, Qunwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284820/
https://www.ncbi.nlm.nih.gov/pubmed/35841005
http://dx.doi.org/10.1186/s13287-022-02995-w

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