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Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases

BACKGROUND: Malignant ‘triton’ tumor is an extremely rare subtype of malignant periphery nerve sheath tumors. Clinical diagnosis of malignant triton tumor is difficult before surgery due to its low incidence and the lack of knowledge. Therefore, to describe and summarize the CT imaging characteristi...

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Autores principales: Li, Yuan, Peng, Qiling, Jiang, Ning, Molloy, David P., Zeng, Chun, Wu, Qingchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284860/
https://www.ncbi.nlm.nih.gov/pubmed/35836141
http://dx.doi.org/10.1186/s12880-022-00848-9
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author Li, Yuan
Peng, Qiling
Jiang, Ning
Molloy, David P.
Zeng, Chun
Wu, Qingchen
author_facet Li, Yuan
Peng, Qiling
Jiang, Ning
Molloy, David P.
Zeng, Chun
Wu, Qingchen
author_sort Li, Yuan
collection PubMed
description BACKGROUND: Malignant ‘triton’ tumor is an extremely rare subtype of malignant periphery nerve sheath tumors. Clinical diagnosis of malignant triton tumor is difficult before surgery due to its low incidence and the lack of knowledge. Therefore, to describe and summarize the CT imaging characteristics of malignant triton tumor is of great assistance for early and preoperative diagnosis. CASE PRESENTATION: Two cases suspected of MTT by CT scan before operation were closely observed. The diagnosis of malignant triton tumor was eventually confirmed by immunochemical assay, which verified speculation of CT scans. Huge, irregular, well-circumscribed lobulated mass-like shadows can be observed from these patients by CT scans. Besides, heterogeneity of density within the body of tumor was well-established by CT scans, together with linear septum. Meanwhile, CT scans demonstrated that calcifications were remarkable at the margin of tumor body. CONCLUSIONS: Some CT image features from two cases were presented as a reference for the preoperative consideration of MTT: (i) enormity of mass-like shadow; (ii) presence of well-circumscribed lobulated shape; (iii) septum within the well-defined mass accompanied with hemorrhage, necrosis and cystic changes as well as calcification, especially within neurofibromatosis type 1 patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12880-022-00848-9.
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spelling pubmed-92848602022-07-16 Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases Li, Yuan Peng, Qiling Jiang, Ning Molloy, David P. Zeng, Chun Wu, Qingchen BMC Med Imaging Case Report BACKGROUND: Malignant ‘triton’ tumor is an extremely rare subtype of malignant periphery nerve sheath tumors. Clinical diagnosis of malignant triton tumor is difficult before surgery due to its low incidence and the lack of knowledge. Therefore, to describe and summarize the CT imaging characteristics of malignant triton tumor is of great assistance for early and preoperative diagnosis. CASE PRESENTATION: Two cases suspected of MTT by CT scan before operation were closely observed. The diagnosis of malignant triton tumor was eventually confirmed by immunochemical assay, which verified speculation of CT scans. Huge, irregular, well-circumscribed lobulated mass-like shadows can be observed from these patients by CT scans. Besides, heterogeneity of density within the body of tumor was well-established by CT scans, together with linear septum. Meanwhile, CT scans demonstrated that calcifications were remarkable at the margin of tumor body. CONCLUSIONS: Some CT image features from two cases were presented as a reference for the preoperative consideration of MTT: (i) enormity of mass-like shadow; (ii) presence of well-circumscribed lobulated shape; (iii) septum within the well-defined mass accompanied with hemorrhage, necrosis and cystic changes as well as calcification, especially within neurofibromatosis type 1 patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12880-022-00848-9. BioMed Central 2022-07-14 /pmc/articles/PMC9284860/ /pubmed/35836141 http://dx.doi.org/10.1186/s12880-022-00848-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Li, Yuan
Peng, Qiling
Jiang, Ning
Molloy, David P.
Zeng, Chun
Wu, Qingchen
Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_full Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_fullStr Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_full_unstemmed Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_short Computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
title_sort computed tomography imaging features of malignant ‘triton’ tumor to facilitate its clinical diagnosis: report of two cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284860/
https://www.ncbi.nlm.nih.gov/pubmed/35836141
http://dx.doi.org/10.1186/s12880-022-00848-9
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