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Ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents
Bilateral ovarian epithelial neoplasms in adolescents are rare. Moreover, borderline mucinous neoplasms with local intraepithelial carcinoma with anaplastic carcinoma are even more infrequent. Herein, we presented a single case (a 17-year-old female) with regular menstrual cycles and stomach pain wh...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284891/ https://www.ncbi.nlm.nih.gov/pubmed/35836292 http://dx.doi.org/10.1186/s13048-022-01010-3 |
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author | Huang, Mengqi Lv, Qian Xie, Jingyan |
author_facet | Huang, Mengqi Lv, Qian Xie, Jingyan |
author_sort | Huang, Mengqi |
collection | PubMed |
description | Bilateral ovarian epithelial neoplasms in adolescents are rare. Moreover, borderline mucinous neoplasms with local intraepithelial carcinoma with anaplastic carcinoma are even more infrequent. Herein, we presented a single case (a 17-year-old female) with regular menstrual cycles and stomach pain when eating who was diagnosed with a left ovarian tumor accompanied by mural nodules. The right ovarian cyst, the left ovary, and the fallopian tube were removed by surgery. Intraoperative diagnosis suggested a bilateral ovarian tumor with mural nodules, which include three different pathological types: sarcomatoid transformation, anaplastic carcinoma, and sarcoma. Paclitaxel combined with carboplatin was given for 6 cycles after an operation, and gonadotropin-releasing hormone agonist (GnRHa) was given at the beginning of chemotherapy for 3 cycles for ovarian function protection. Regular follow-up (the last follow-up was performed 48 months after the operation) of gynecological ultrasound and tumor indicators did not indicate recurrence. In clinical practice, it is necessary to pay attention to the symptoms such as abdominal pain in adolescent females. Routine non-invasive pelvic ultrasound is recommended to fully evaluate the nature of the tumor before surgery, and decide the operation mode. Also, intraoperative frozen pathology of the tissue should be performed as soon as possible. |
format | Online Article Text |
id | pubmed-9284891 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-92848912022-07-16 Ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents Huang, Mengqi Lv, Qian Xie, Jingyan J Ovarian Res Case Report Bilateral ovarian epithelial neoplasms in adolescents are rare. Moreover, borderline mucinous neoplasms with local intraepithelial carcinoma with anaplastic carcinoma are even more infrequent. Herein, we presented a single case (a 17-year-old female) with regular menstrual cycles and stomach pain when eating who was diagnosed with a left ovarian tumor accompanied by mural nodules. The right ovarian cyst, the left ovary, and the fallopian tube were removed by surgery. Intraoperative diagnosis suggested a bilateral ovarian tumor with mural nodules, which include three different pathological types: sarcomatoid transformation, anaplastic carcinoma, and sarcoma. Paclitaxel combined with carboplatin was given for 6 cycles after an operation, and gonadotropin-releasing hormone agonist (GnRHa) was given at the beginning of chemotherapy for 3 cycles for ovarian function protection. Regular follow-up (the last follow-up was performed 48 months after the operation) of gynecological ultrasound and tumor indicators did not indicate recurrence. In clinical practice, it is necessary to pay attention to the symptoms such as abdominal pain in adolescent females. Routine non-invasive pelvic ultrasound is recommended to fully evaluate the nature of the tumor before surgery, and decide the operation mode. Also, intraoperative frozen pathology of the tissue should be performed as soon as possible. BioMed Central 2022-07-14 /pmc/articles/PMC9284891/ /pubmed/35836292 http://dx.doi.org/10.1186/s13048-022-01010-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Huang, Mengqi Lv, Qian Xie, Jingyan Ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents |
title | Ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents |
title_full | Ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents |
title_fullStr | Ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents |
title_full_unstemmed | Ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents |
title_short | Ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents |
title_sort | ovarian mucinous borderline tumor with anaplastic carcinomatous nodules in adolescents |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284891/ https://www.ncbi.nlm.nih.gov/pubmed/35836292 http://dx.doi.org/10.1186/s13048-022-01010-3 |
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