Metformin combats high glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells via inhibition of the NPR3-mediated MAPK pathway

BACKGROUND: High glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells (PDLSCs) has long been a challenge to periodontal regeneration for diabetic individuals. Metformin is an anti-hyperglycemic drug that exhibits abundant biological activities associated...

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Detalles Bibliográficos
Autores principales: Zhang, Yi-Lin, Liu, Fen, Li, Zhi-Bang, He, Xiao-Tao, Li, Xuan, Wu, Rui-Xin, Sun, Hai-Hua, Ge, Shao-Hua, Chen, Fa-Ming, An, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284897/
https://www.ncbi.nlm.nih.gov/pubmed/35841070
http://dx.doi.org/10.1186/s13287-022-02992-z

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