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Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022

A monkeypox (MPX) outbreak has expanded worldwide since May 2022. We tested 147 clinical samples collected at different time points from 12 patients by real-time PCR. MPX DNA was detected in saliva from all cases, sometimes with high viral loads. Other samples were frequently positive: rectal swab (...

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Autores principales: Peiró-Mestres, Aida, Fuertes, Irene, Camprubí-Ferrer, Daniel, Marcos, María Ángeles, Vilella, Anna, Navarro, Mireia, Rodriguez-Elena, Laura, Riera, Josep, Català, Alba, Martínez, Miguel J, Blanco, Jose L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284919/
https://www.ncbi.nlm.nih.gov/pubmed/35837964
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.28.2200503
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author Peiró-Mestres, Aida
Fuertes, Irene
Camprubí-Ferrer, Daniel
Marcos, María Ángeles
Vilella, Anna
Navarro, Mireia
Rodriguez-Elena, Laura
Riera, Josep
Català, Alba
Martínez, Miguel J
Blanco, Jose L
author_facet Peiró-Mestres, Aida
Fuertes, Irene
Camprubí-Ferrer, Daniel
Marcos, María Ángeles
Vilella, Anna
Navarro, Mireia
Rodriguez-Elena, Laura
Riera, Josep
Català, Alba
Martínez, Miguel J
Blanco, Jose L
author_sort Peiró-Mestres, Aida
collection PubMed
description A monkeypox (MPX) outbreak has expanded worldwide since May 2022. We tested 147 clinical samples collected at different time points from 12 patients by real-time PCR. MPX DNA was detected in saliva from all cases, sometimes with high viral loads. Other samples were frequently positive: rectal swab (11/12 cases), nasopharyngeal swab (10/12 cases), semen (7/9 cases), urine (9/12 cases) and faeces (8/12 cases). These results improve knowledge on virus shedding and the possible role of bodily fluids in disease transmission.
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spelling pubmed-92849192022-07-28 Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022 Peiró-Mestres, Aida Fuertes, Irene Camprubí-Ferrer, Daniel Marcos, María Ángeles Vilella, Anna Navarro, Mireia Rodriguez-Elena, Laura Riera, Josep Català, Alba Martínez, Miguel J Blanco, Jose L Euro Surveill Rapid Communication A monkeypox (MPX) outbreak has expanded worldwide since May 2022. We tested 147 clinical samples collected at different time points from 12 patients by real-time PCR. MPX DNA was detected in saliva from all cases, sometimes with high viral loads. Other samples were frequently positive: rectal swab (11/12 cases), nasopharyngeal swab (10/12 cases), semen (7/9 cases), urine (9/12 cases) and faeces (8/12 cases). These results improve knowledge on virus shedding and the possible role of bodily fluids in disease transmission. European Centre for Disease Prevention and Control (ECDC) 2022-07-14 /pmc/articles/PMC9284919/ /pubmed/35837964 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.28.2200503 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Peiró-Mestres, Aida
Fuertes, Irene
Camprubí-Ferrer, Daniel
Marcos, María Ángeles
Vilella, Anna
Navarro, Mireia
Rodriguez-Elena, Laura
Riera, Josep
Català, Alba
Martínez, Miguel J
Blanco, Jose L
Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022
title Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022
title_full Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022
title_fullStr Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022
title_full_unstemmed Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022
title_short Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022
title_sort frequent detection of monkeypox virus dna in saliva, semen, and other clinical samples from 12 patients, barcelona, spain, may to june 2022
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9284919/
https://www.ncbi.nlm.nih.gov/pubmed/35837964
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.28.2200503
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