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Cyclocytidine hydrochloride inhibits the synthesis of relaxed circular DNA of hepatitis B virus

BACKGROUND: Cyclocytidine hydrochloride (HCl) has been reported to inhibit DNA synthesis by affecting DNA polymerase. Here, we tested the antiviral effect of cyclocytidine on hepatitis B virus (HBV) DNA synthesis, which is reliant on DNA polymerase activity. MATERIALS AND METHODS: Cyclocytidine HCl...

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Detalles Bibliográficos
Autores principales:	Wang, Xue, Xiao, Yihan, Cui, Zhigang, Li, Zongxin, Li, Lihua, Wu, Lixian, Yin, Feifei, Cui, Xiuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285472/ https://www.ncbi.nlm.nih.gov/pubmed/35846878 http://dx.doi.org/10.7717/peerj.13719

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