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Allopregnanolone: An overview on its synthesis and effects
Allopregnanolone, a 3α,5α‐progesterone metabolite, acts as a potent allosteric modulator of the γ‐aminobutyric acid type A receptor. In the present review, the synthesis of this neuroactive steroid occurring in the nervous system is discussed with respect to physiological and pathological conditions...
Autores principales: | Diviccaro, Silvia, Cioffi, Lucia, Falvo, Eva, Giatti, Silvia, Melcangi, Roberto Cosimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285581/ https://www.ncbi.nlm.nih.gov/pubmed/34189791 http://dx.doi.org/10.1111/jne.12996 |
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