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Allopregnanolone: An overview on its synthesis and effects

Allopregnanolone, a 3α,5α‐progesterone metabolite, acts as a potent allosteric modulator of the γ‐aminobutyric acid type A receptor. In the present review, the synthesis of this neuroactive steroid occurring in the nervous system is discussed with respect to physiological and pathological conditions...

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Detalles Bibliográficos
Autores principales: Diviccaro, Silvia, Cioffi, Lucia, Falvo, Eva, Giatti, Silvia, Melcangi, Roberto Cosimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285581/
https://www.ncbi.nlm.nih.gov/pubmed/34189791
http://dx.doi.org/10.1111/jne.12996

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