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Application of inline variable pathlength technology for rapid determination of dynamic binding capacity in downstream process development of biopharmaceuticals

Determination of dynamic binding capacity (DBC) for capture purification chromatographic step is usually the first experiment to be performed during downstream process development of biopharmaceuticals. In this work, we investigated the application of inline variable pathlength technology using Flow...

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Detalles Bibliográficos
Autores principales: Bhangale, Rashmi P., Ye, Rui, Lindsey, Thomas B., Wolfe, Leslie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285919/
https://www.ncbi.nlm.nih.gov/pubmed/35064963
http://dx.doi.org/10.1002/btpr.3236

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