Molecular weight determination of adeno‐associate virus serotype 8 virus‐like particle either carrying or lacking genome via native nES gas‐phase electrophoretic molecular mobility analysis and nESI QRTOF mass spectrometry

Virus‐like particles (VLPs) are proteinaceous shells derived from viruses lacking any viral genomic material. Adeno‐associated virus (AAV) is a non‐enveloped icosahedral virus used as VLP delivery system in gene therapy (GT). Its success as vehicle for GT is due to its selective tropism, high level...

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Detalles Bibliográficos
Autores principales: Zoratto, Samuele, Weiss, Victor U., van der Horst, Jerre, Commandeur, Jan, Buengener, Carsten, Foettinger‐Vacha, Alexandra, Pletzenauer, Robert, Graninger, Michael, Allmaier, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9285973/
https://www.ncbi.nlm.nih.gov/pubmed/34608711
http://dx.doi.org/10.1002/jms.4786

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