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Enhanced phosphate absorption in intestinal epithelial cell‐specific NHE3 knockout mice

AIMS: The kidneys play a major role in maintaining P(i) homeostasis. Patients in later stages of CKD develop hyperphosphatemia. One novel treatment option is tenapanor, an intestinal‐specific NHE3 inhibitor. To gain mechanistic insight into the role of intestinal NHE3 in P(i) homeostasis, we studied...

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Detalles Bibliográficos
Autores principales:	Xue, Jianxiang, Thomas, Linto, Murali, Sathish Kumar, Levi, Moshe, Fenton, Robert A., Dominguez Rieg, Jessica A., Rieg, Timo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Gastrointestinal Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286053/ https://www.ncbi.nlm.nih.gov/pubmed/34978760 http://dx.doi.org/10.1111/apha.13756

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