Coordinated modulation of multiple processes through phase variation of a c-di-GMP phosphodiesterase in Clostridioides difficile

The opportunistic nosocomial pathogen Clostridioides difficile exhibits phenotypic heterogeneity through phase variation, a stochastic, reversible process that modulates expression. In C. difficile, multiple sequences in the genome undergo inversion through site-specific recombination. Two such loci...

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Detalles Bibliográficos
Autores principales: Reyes Ruiz, Leila M., King, Kathleen A., Agosto-Burgos, Christian, Gamez, Isabella S., Gadda, Nicole C., Garrett, Elizabeth M., Tamayo, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286219/
https://www.ncbi.nlm.nih.gov/pubmed/35789350
http://dx.doi.org/10.1371/journal.ppat.1010677

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