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In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution

Leishmania parasites cause cutaneous leishmaniasis (CL), a disease characterized by disfiguring, ulcerative skin lesions. Both parasite and host gene expression following infection with various Leishmania species has been investigated in vitro, but global transcriptional analysis following L. major...

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Detalles Bibliográficos
Autores principales: Venugopal, Gopinath, Bird, Jordan T., Washam, Charity L., Roys, Hayden, Bowlin, Anne, Byrum, Stephanie D., Weinkopff, Tiffany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286232/
https://www.ncbi.nlm.nih.gov/pubmed/35789215
http://dx.doi.org/10.1371/journal.pntd.0010518