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Association of cytochromes P450 3A422 and 3A53 genotypes and polymorphism with response to simvastatin in hypercholesterolemia patients

BACKGROUNDS: Inter-individual variability in response to statin was mainly due to genetic differences. This study aimed to investigate the association of CYP3A4*22 (rs35599367), CYP3A5*3 (rs776746) single nucleotide polymorphism (SNP) with response to simvastatin in hypercholesterolemia patients con...

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Detalles Bibliográficos
Autores principales:	Elalem, Elbatool G., Jelani, Musharraf, Khedr, Alaa, Ahmad, Aftab, Alaama, Tareef Y., Alaama, Mohamed Nabeel, Al-Kreathy, Huda M., Damanhouri, Zoheir A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286239/ https://www.ncbi.nlm.nih.gov/pubmed/35839255 http://dx.doi.org/10.1371/journal.pone.0260824

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