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Uncomplicated oocyte donation pregnancies display an elevated CD163‐positive type 2 macrophage load in the decidua, which is associated with fetal‐maternal HLA mismatches
PROBLEM: The embryo of an oocyte donation (OD) pregnancy is completely allogeneic to the mother, which may challenge the maternal immune system to tolerize the fetus. Decidual macrophages are essential in maintaining a healthy pregnancy, and type 2 macrophages may exhibit immune suppressive activity...
Autores principales: | Tian, Xuezi, Aiyer, Kaveri T. S., Kapsenberg, Johanna M., Roelen, Dave L., van der Hoorn, Marie‐Louise, Eikmans, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286476/ https://www.ncbi.nlm.nih.gov/pubmed/34738274 http://dx.doi.org/10.1111/aji.13511 |
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