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Modeling Macrophage Polarization and Its Effect on Cancer Treatment Success
Positive feedback loops drive immune cell polarization toward a pro-tumor phenotype that accentuates immunosuppression and tumor angiogenesis. This phenotypic switch leads to the escape of cancer cells from immune destruction. These positive feedback loops are generated by cytokines such as TGF-β, I...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286492/ https://www.ncbi.nlm.nih.gov/pubmed/35847834 http://dx.doi.org/10.4236/oji.2018.82004 |