Pluripotency factors regulate the onset of Hox cluster activation in the early embryo

Pluripotent cells are a transient population of the mammalian embryo dependent on transcription factors, such as OCT4 and NANOG, which maintain pluripotency while suppressing lineage specification. However, these factors are also expressed during early phases of differentiation, and their role in th...

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Detalles Bibliográficos
Autores principales: Tiana, María, Lopez-Jimenez, Elena, de Aja, Julio Sainz, Barral, Antonio, Victorino, Jesus, Badia-Careaga, Claudio, Rollan, Isabel, Rouco, Raquel, Santos, Elisa, Sanchez-Iranzo, Hector, Acemel, Rafael D., Torroja, Carlos, Adan, Javier, Andres-Leon, Eduardo, Gomez-Skarmeta, Jose Luis, Giovinazzo, Giovanna, Sanchez-Cabo, Fatima, Manzanares, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286507/
https://www.ncbi.nlm.nih.gov/pubmed/35857513
http://dx.doi.org/10.1126/sciadv.abo3583

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