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Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry

RATIONALE: Fully formulated oils (FFOs) are integral to automotive lubrication; however, detailed compositional analysis is challenging due to high levels of chemical complexity. In particular, existing mass spectrometric approaches often target particular FFO components, leading to poor analytical...

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Autores principales: Basham, Vincent, Hancock, Tom, McKendrick, John, Tessarolo, Nathalia, Wicking, Chrissie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286547/
https://www.ncbi.nlm.nih.gov/pubmed/35484791
http://dx.doi.org/10.1002/rcm.9320
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author Basham, Vincent
Hancock, Tom
McKendrick, John
Tessarolo, Nathalia
Wicking, Chrissie
author_facet Basham, Vincent
Hancock, Tom
McKendrick, John
Tessarolo, Nathalia
Wicking, Chrissie
author_sort Basham, Vincent
collection PubMed
description RATIONALE: Fully formulated oils (FFOs) are integral to automotive lubrication; however, detailed compositional analysis is challenging due to high levels of chemical complexity. In particular, existing mass spectrometric approaches often target particular FFO components, leading to poor analytical coverage of the overall formulation, with increased overheads and analytical timescales. METHODS: Herein we report the application of a commercially available SICRIT SC‐20 dielectric barrier discharge ionisation (DBDI) source and Thermo Fisher Scientific LTQ Orbitrap XL to the analysis of an FFO. Nitrogen was used as a discharge gas for the DBDI source, and was modified using a range of commonplace solvents to tailor the experimental conditions for the analysis of various components. RESULTS: The reported method allowed analysis of a range of FFO components of interest, encompassing a wide range of chemistries, in under 1 min. By modifying the discharge gas used for ionisation, experiments could be optimised for the analysis of particular FFO components across positive and negative ion modes. In particular, use of water vapour as a discharge gas modifier with positive ion mode mass spectrometry permitted concomitant analysis of antioxidants and base oil hydrocarbons. Furthermore, case studies of selected linear alkanes and alkenes profile the differences in the range of ions formed across these saturated and unsaturated aliphatic compounds, giving insight into the fate of base oil hydrocarbons in FFO analyses. CONCLUSIONS: A rapid method for analysis of FFO compositions has been developed and provides coverage of a range of components of interest. The results indicate that the method presented may be of utility in analysis of other FFOs or similarly challenging complex mixtures.
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spelling pubmed-92865472022-07-19 Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry Basham, Vincent Hancock, Tom McKendrick, John Tessarolo, Nathalia Wicking, Chrissie Rapid Commun Mass Spectrom Research Articles RATIONALE: Fully formulated oils (FFOs) are integral to automotive lubrication; however, detailed compositional analysis is challenging due to high levels of chemical complexity. In particular, existing mass spectrometric approaches often target particular FFO components, leading to poor analytical coverage of the overall formulation, with increased overheads and analytical timescales. METHODS: Herein we report the application of a commercially available SICRIT SC‐20 dielectric barrier discharge ionisation (DBDI) source and Thermo Fisher Scientific LTQ Orbitrap XL to the analysis of an FFO. Nitrogen was used as a discharge gas for the DBDI source, and was modified using a range of commonplace solvents to tailor the experimental conditions for the analysis of various components. RESULTS: The reported method allowed analysis of a range of FFO components of interest, encompassing a wide range of chemistries, in under 1 min. By modifying the discharge gas used for ionisation, experiments could be optimised for the analysis of particular FFO components across positive and negative ion modes. In particular, use of water vapour as a discharge gas modifier with positive ion mode mass spectrometry permitted concomitant analysis of antioxidants and base oil hydrocarbons. Furthermore, case studies of selected linear alkanes and alkenes profile the differences in the range of ions formed across these saturated and unsaturated aliphatic compounds, giving insight into the fate of base oil hydrocarbons in FFO analyses. CONCLUSIONS: A rapid method for analysis of FFO compositions has been developed and provides coverage of a range of components of interest. The results indicate that the method presented may be of utility in analysis of other FFOs or similarly challenging complex mixtures. John Wiley and Sons Inc. 2022-05-16 2022-07-30 /pmc/articles/PMC9286547/ /pubmed/35484791 http://dx.doi.org/10.1002/rcm.9320 Text en © 2022 The Authors. Rapid Communications in Mass Spectrometry published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Basham, Vincent
Hancock, Tom
McKendrick, John
Tessarolo, Nathalia
Wicking, Chrissie
Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry
title Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry
title_full Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry
title_fullStr Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry
title_full_unstemmed Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry
title_short Detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry
title_sort detailed chemical analysis of a fully formulated oil using dielectric barrier discharge ionisation–mass spectrometry
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286547/
https://www.ncbi.nlm.nih.gov/pubmed/35484791
http://dx.doi.org/10.1002/rcm.9320
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