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Quantitative system pharmacology as a legitimate approach to examine extrapolation strategies used to support pediatric drug development
Extrapolation strategies from adult data for designing pediatric drug development programs are explored using the quantitative systems pharmacology (QSP) modeling approach, a mechanistic drug and disease modeling framework that can predict clinical response and guide pediatric drug development in ge...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286717/ https://www.ncbi.nlm.nih.gov/pubmed/35411657 http://dx.doi.org/10.1002/psp4.12801 |