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Genetic dissection of the RNA polymerase II transcription cycle

How DNA sequence affects the dynamics and position of RNA Polymerase II (Pol II) during transcription remains poorly understood. Here, we used naturally occurring genetic variation in F1 hybrid mice to explore how DNA sequence differences affect the genome-wide distribution of Pol II. We measured th...

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Detalles Bibliográficos
Autores principales: Chou, Shao-Pei, Alexander, Adriana K, Rice, Edward J, Choate, Lauren A, Danko, Charles G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286732/
https://www.ncbi.nlm.nih.gov/pubmed/35775732
http://dx.doi.org/10.7554/eLife.78458