Synaptic location is a determinant of the detrimental effects of α-synuclein pathology to glutamatergic transmission in the basolateral amygdala

The presynaptic protein α-synuclein (αSyn) has been suggested to be involved in the pathogenesis of Parkinson’s disease (PD). In PD, the amygdala is prone to develop insoluble αSyn aggregates, and it has been suggested that circuit dysfunction involving the amygdala contributes to the psychiatric sy...

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Detalles Bibliográficos
Autores principales: Chen, Liqiang, Nagaraja, Chetan, Daniels, Samuel, Fisk, Zoe A, Dvorak, Rachel, Meyerdirk, Lindsay, Steiner, Jennifer A, Escobar Galvis, Martha L, Henderson, Michael X, Rousseaux, Maxime WC, Brundin, Patrik, Chu, Hong-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286736/
https://www.ncbi.nlm.nih.gov/pubmed/35775627
http://dx.doi.org/10.7554/eLife.78055

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