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Mutant-Allele Tumor Heterogeneity, a Favorable Biomarker to Assess Intra-Tumor Heterogeneity, in Advanced Lung Adenocarcinoma

BACKGROUND: Intra-tumor heterogeneity (ITH) plays a vital role in drug resistance and recurrence of lung cancer. We used a mutant-allele tumor heterogeneity (MATH) algorithm to assess ITH and investigated its association with clinical and molecular features in advanced lung adenocarcinoma. METHODS:...

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Detalles Bibliográficos
Autores principales:	Wu, Xiaoxuan, Song, Peng, Guo, Lei, Ying, Jianming, Li, Wenbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286753/ https://www.ncbi.nlm.nih.gov/pubmed/35847947 http://dx.doi.org/10.3389/fonc.2022.888951

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