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Towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning
OBJECTIVE: In routine oncological treatment settings, psychological distress, including mental disorders, is overlooked in 30% to 50% of patients. High workload and a constant need to optimise time and costs require a quick and easy method to identify patients likely to miss out on psychological sup...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286797/ https://www.ncbi.nlm.nih.gov/pubmed/35137480 http://dx.doi.org/10.1111/ecc.13555 |
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author | Günther, Moritz Philipp Kirchebner, Johannes Schulze, Jan Ben von Känel, Roland Euler, Sebastian |
author_facet | Günther, Moritz Philipp Kirchebner, Johannes Schulze, Jan Ben von Känel, Roland Euler, Sebastian |
author_sort | Günther, Moritz Philipp |
collection | PubMed |
description | OBJECTIVE: In routine oncological treatment settings, psychological distress, including mental disorders, is overlooked in 30% to 50% of patients. High workload and a constant need to optimise time and costs require a quick and easy method to identify patients likely to miss out on psychological support. METHODS: Using machine learning, factors associated with no consultation with a clinical psychologist or psychiatrist were identified between 2011 and 2019 in 7,318 oncological patients in a large cancer treatment centre. Parameters were hierarchically ordered based on statistical relevance. Nested resampling and cross validation were performed to avoid overfitting. RESULTS: Patients were least likely to receive psycho‐oncological (i.e., psychiatric/psychotherapeutic) treatment when they were not formally screened for distress, had inpatient treatment for less than 28 days, had no psychiatric diagnosis, were aged 65 or older, had skin cancer or were not being discussed in a tumour board. The final validated model was optimised to maximise sensitivity at 85.9% and achieved an area under the curve (AUC) of 0.75, a balanced accuracy of 68.5% and specificity of 51.2%. CONCLUSION: Beyond conventional screening tools, results might contribute to identify patients at risk to be neglected in terms of referral to psycho‐oncology within routine oncological care. |
format | Online Article Text |
id | pubmed-9286797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92867972022-07-19 Towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning Günther, Moritz Philipp Kirchebner, Johannes Schulze, Jan Ben von Känel, Roland Euler, Sebastian Eur J Cancer Care (Engl) Original Articles OBJECTIVE: In routine oncological treatment settings, psychological distress, including mental disorders, is overlooked in 30% to 50% of patients. High workload and a constant need to optimise time and costs require a quick and easy method to identify patients likely to miss out on psychological support. METHODS: Using machine learning, factors associated with no consultation with a clinical psychologist or psychiatrist were identified between 2011 and 2019 in 7,318 oncological patients in a large cancer treatment centre. Parameters were hierarchically ordered based on statistical relevance. Nested resampling and cross validation were performed to avoid overfitting. RESULTS: Patients were least likely to receive psycho‐oncological (i.e., psychiatric/psychotherapeutic) treatment when they were not formally screened for distress, had inpatient treatment for less than 28 days, had no psychiatric diagnosis, were aged 65 or older, had skin cancer or were not being discussed in a tumour board. The final validated model was optimised to maximise sensitivity at 85.9% and achieved an area under the curve (AUC) of 0.75, a balanced accuracy of 68.5% and specificity of 51.2%. CONCLUSION: Beyond conventional screening tools, results might contribute to identify patients at risk to be neglected in terms of referral to psycho‐oncology within routine oncological care. John Wiley and Sons Inc. 2022-02-09 2022-03 /pmc/articles/PMC9286797/ /pubmed/35137480 http://dx.doi.org/10.1111/ecc.13555 Text en © 2022 The Authors. European Journal of Cancer Care published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Günther, Moritz Philipp Kirchebner, Johannes Schulze, Jan Ben von Känel, Roland Euler, Sebastian Towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning |
title | Towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning |
title_full | Towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning |
title_fullStr | Towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning |
title_full_unstemmed | Towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning |
title_short | Towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning |
title_sort | towards identifying cancer patients at risk to miss out on psycho‐oncological treatment via machine learning |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286797/ https://www.ncbi.nlm.nih.gov/pubmed/35137480 http://dx.doi.org/10.1111/ecc.13555 |
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